ANTI-MIGRATORY EFFECT OF VINFLUNINE IN ENDOTHELIAL AND GLIOBLASTOMA CELLS IS ASSOCIATED WITH CHANGES IN EB1 C-TERMINAL DETYROSINATED/TYROSINATED STATUS.

We previously showed that vinflunine, a microtubule-targeting drug of the Vinca-alkaloid family exerted its anti-angiogenic/anti-migratory activities through an increase in microtubule dynamics and an inhibition of microtubule Candles targeting to adhesion sites.Such effect was associated with a reduction of EB1 comet length at microtubule (+) ends

In liquid Candles argon time projection chambers exposed to neutrino beams and running on or near surface levels, cosmic muons, and other cosmic particles are incident on the detectors while a single neutrino-induced event is being recorded.In practice, this means that data from surface liquid argon time projection chambers will be dominated by cos

Pedestrian detection is widely used in real-time surveillance, urban traffic, and other fields.As a crucial direction in pedestrian detection, dense pedestrian detection still faces many unresolved challenges.Existing methods suffer from low detection accuracy, high miss rates, large model parameters, and poor robustness.In this paper, to address t

Steering Wheel Hub Adapters Cardial troponin I concentration and creatine phosphokinase MB activity in blood serum was investigated in 63 neonates during the neonatal period.It was revealed that clinical symptoms of myocardial lesions manifest themselves as vegetovisceral disorders in premature neonates.The level of cardiac specific markers depends